Evidence Synthesis in Real-Time
Explainable AI for the life sciences that turns months of manual literature review into days, with audit-grade provenance every step of the way.
From Protocol to Evidence in Six Phases
The complete systematic review workflow, powered by explainable AI.
Phase 1: Planning & Protocol
The most critical phase of any systematic review. If the protocol leaves room for interpretation, downstream AI and human decisions will be inconsistent. Puraite provides a guided wizard that walks you step by step through protocol creation – simply fill in the fields without having to set up the protocol manually. It flags ambiguous criteria in real time so every inclusion rule is precise before screening begins.
Who Puraite Is Made For
Regulated industries where the speed, auditability, and reproducibility of evidence synthesis directly determine commercial and regulatory outcomes.
Free for Academia
Puraite is available at no cost for university researchers and non-commercial systematic review teams. Rigorous evidence synthesis should not be gated by budget.
Academic accounts come with limited monthly usage. For high-volume research groups, tailored plans are available on request.
Where Do You Stand on SLR Automation?
See how AI-powered evidence synthesis compares to your current workflow.
Industry benchmark: a standard systematic review with 5 co-authors over 16 months costs approximately €165,000 in researcher time. Costs scale proportionally with team size and project duration.
Why Puraite
Four capabilities that set Puraite apart from generic AI tools and legacy SLR platforms.
Every decision, traced to source.
Every AI screening decision links directly to the sentence that drove it, with a calibrated confidence score. No black box. No trust-us outputs. Auditable at every step.
Built for submission, not just discovery.
PRISMA flow diagrams, GRADE certainty ratings and RoB assessments are generated automatically with complete decision logs, ready for HTA, MDR CER or FDA dossier.
You decide. AI recommends.
Approve, override, comment or escalate any AI action at any stage. Puraite augments your team's judgment; it never replaces it. All overrides are logged and exportable.
One digital workspace. Zero media breaks.
Protocol to PRISMA report, every step lives inside one auditable environment. No switching tools, no copy-paste. Activate AI at any step or work entirely manually.
Built for Regulated Environments
Every AI decision is transparent, traceable and auditable.
Citation-Level Provenance
Every output traced to its source passage
Confidence Scoring
Calibrated 1–100% certainty on every decision
Complete Audit Trails
Full decision logs for regulatory review
Human Control Plane
Approve, override or escalate any AI decision
Engineering Rigor
How we build, validate and deploy AI for regulated evidence synthesis.
Validated against gold-standard evidence
Every AI module is benchmarked against expert-curated systematic review datasets. Screening decisions are validated against Cochrane-quality inclusion sets. We measure recall, precision and calibration continuously, not just at launch. Joint publications with independent academic researchers are underway and scheduled for publication in Q3/Q4 2026.
Selecting the right model for each task
We benchmark leading foundation models across every pipeline stage: retrieval, screening, extraction and synthesis. Model selection is task-specific. A model that excels at eligibility classification may underperform at data extraction. We fine-tune and specialize models for domain-specific tasks such as HEOR dossier preparation, clinical data extraction and regulatory evidence appraisal. This allows us to deploy the most capable model for each step at the lowest cost and energy consumption.
Calibrated confidence, not black-box predictions
Our screening engine uses conformal prediction to deliver statistically guaranteed coverage rates. Every decision includes a confidence score with known error bounds. When the AI is uncertain, it flags the record for human review instead of guessing.
What's Coming Next
Puraite is building toward a fully autonomous, continuously learning evidence platform. Here's what's on the horizon.
Living Evidence Platform
Systematic reviews that update automatically as new literature publishes. No re-runs, no re-screening; your evidence base stays current.
Shapley Attribution
Know exactly which studies drove every meta-analytic conclusion. Game-theoretic attribution surfaces the evidence that matters most, and why.
Evidence Studio
Collaborative workspace for distributed review teams. Real-time conflict resolution, annotation and consensus workflows built for multi-site trials.
Evidence Orchestrator
A multi-agent pipeline that autonomously searches, screens, extracts and synthesizes; fully auditable, with human checkpoints at every critical junction.
Want early access to upcoming features?
Talk to the Team