Trusted by enterprise teams in Pharma and MedTech

EvidenceSynthesisinReal-Time

Explainable AI for the life sciences that turns months of manual literature review into days, with audit-grade provenance every step of the way.

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Screening Accuracy
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From Protocol to Report

Supported by Europe's leading AI and life science organisations

From Protocol to Evidence in Six Phases

The complete systematic review workflow, powered by explainable AI.

P
Puraite
Systematic reviews
A systematic revi...
Workflow
Planning
Research Question
Scoping Search
Protocol Editor
Registration
Search
Search Strategy
Database Search
Grey Literature
Deduplication
Screening
TIAB Screening
TIAB Conflicts
Full-Text Retrieval
Full-Text Screening
FT Conflicts
Extraction
Extraction Form
Data Extraction
Risk of Bias
Conflicts
Author Contact
Synthesis
Meta-Analysis
Qual. Synthesis
GRADE
SoF Tables
Reporting
PRISMA Draft
Flow Diagram
Living Review
Admin
Project Config
Notifications
EditorCriteria Board
Protocol Editor
Existing Criteria (23)P: 6I: 4C: 4O: 4A: 5
PolarityCriteriaCategory
EXCLUDEMajor neurological disorder (epilepsy, MS, Parkinson's, TBI)Population
EXCLUDEDiagnosis of major neurocognitive disorder (dementia)Population
INCLUDEFormal diagnosis of major depressive disorder (MDD)Population
INCLUDEAdults aged 50 years or olderPopulation
INCLUDERandomized controlled trial or controlled clinical trialStudy Design
Ambiguity detected
Criterion "Adults aged 50+" may conflict with "older adults" definition. Consider specifying mean vs. individual age.

Phase 1: Planning & Protocol

The most critical phase of any systematic review. If the protocol leaves room for interpretation, downstream AI and human decisions will be inconsistent. Puraite flags ambiguous criteria in real time so every inclusion rule is precise before screening begins. Define your research question using PICO, run scoping searches and lock down the methodology.

Define Research Question (PICO)?
Conduct Scoping Search?
Write the Protocol?
Register Protocol (optional)?

Who Puraite Is Made For

Regulated industries where the speed, auditability, and reproducibility of evidence synthesis directly determine commercial and regulatory outcomes.

Pharmaceuticals

Regulatory Affairs
Systematic reviews and meta-analyses for EMA, FDA and G-BA dossier submissions, built to IQWiG and NICE methodological standards
Market Access & HEOR
Evidence packages for AMNOG dossiers, NICE technology appraisals and multi-market HTA submissions; faster turnaround, defensible methodology
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Medical Devices

Regulatory Affairs
MDR Article 61 / IVDR-compliant clinical evaluation reports with traceable, reproducible literature review methodology
Clinical & Market Access
State-of-the-art documentation, PMCF evidence gap analysis, and equivalence argumentation per MDR Annex XIV
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CRO & Market Access Consultancies

Evidence Synthesis Teams
Run multiple concurrent systematic reviews without proportional headcount increases; AI handles screening, your experts handle judgment
Clinical Operations
White-label evidence outputs in your template; Puraite powers the methodology end-to-end
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Insurance & Payers

Coverage Decisions
Rapid evidence appraisal for formulary reviews, coverage policies and benefit-risk assessments
Health Economics
Structured evidence packages supporting reimbursement negotiations and value frameworks
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Chemistry

Regulatory Safety
Systematic reviews for REACH registration dossiers, chemical safety reports and environmental risk evaluations
Product Compliance
Literature-based safety evidence for substance authorisation, restriction proposals and SVHC assessments
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Food & Nutrition

Regulatory Safety
Systematic reviews for EFSA safety assessments, novel food applications and additive re-evaluations
Product Compliance
Literature-based evidence for health claims substantiation, MRL assessments and dietary exposure modelling
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Cosmetics

Safety Assessment
Systematic literature review for cosmetic ingredient safety evaluation per EU Cosmetics Regulation (EC) No 1223/2009
Claims & Dossiers
SCCS-aligned evidence packages for ingredient safety, claim substantiation, sensitisation and toxicological profiles
Learn more →

Free for Academia

Puraite is available at no cost for university researchers and non-commercial systematic review teams. Rigorous evidence synthesis should not be gated by budget.

Academic accounts come with limited monthly usage. For high-volume research groups, tailored plans are available on request.

Request Academic Accesscontact [at] puraite [dot] com

Where Do You Stand on SLR Automation?

See how AI-powered evidence synthesis compares to your current workflow.

5
1150
5
110
16
324
Current Annual Cost
€825.000
80 months
Potential Savings
€577.500€701.250
up to 85% cost reduction
Time Saved
70 months
up to 85% time reduction

Industry benchmark: a standard systematic review with 5 co-authors over 16 months costs approximately €165,000 in researcher time. Costs scale proportionally with team size and project duration.

Why Puraite

Four capabilities that set Puraite apart from generic AI tools and legacy SLR platforms.

Explainability

Every decision, traced to source.

Every AI screening decision links directly to the sentence that drove it, with a calibrated confidence score. No black box. No trust-us outputs. Auditable at every step.

Regulatory-grade

Built for submission, not just discovery.

PRISMA flow diagrams, GRADE certainty ratings and RoB assessments are generated automatically with complete decision logs, ready for HTA, MDR CER or FDA dossier.

Human control

You decide. AI recommends.

Approve, override, comment or escalate any AI action at any stage. Puraite augments your team's judgment; it never replaces it. All overrides are logged and exportable.

End-to-end

One digital workspace. Zero media breaks.

Protocol to PRISMA report, every step lives inside one auditable environment. No switching tools, no copy-paste. Activate AI at any step or work entirely manually.

Built for Regulated Environments

Every AI decision is transparent, traceable and auditable.

XAI / Transparency Layer
Provenance & Traceability
Rationale & Justification
Confidence Interval 1-100%
Audit & Compliance Outputs
Puraite XAI
Approve
Override
Human Control Plane
Comment
Second Review
Neural Evidence Engine
Protocols
Search Publications
Full-text PDF
Tables
RetrieverClassifierExtractorSynthesizer
Neural Evidence Engine
90% fasterTime-to-Insight
Inclusion Decisions
Extracted Data
Effect Sizes
Evidence Tables

Citation-Level Provenance

Every output traced to its source passage

Confidence Scoring

Calibrated 1–100% certainty on every decision

Complete Audit Trails

Full decision logs for regulatory review

Human Control Plane

Approve, override or escalate any AI decision

Product Roadmap

What's Coming Next

Puraite is building toward a fully autonomous, continuously learning evidence platform. Here's what's on the horizon.

In Development

Living Evidence Platform

Systematic reviews that update automatically as new literature publishes. No re-runs, no re-screening; your evidence base stays current.

Research Phase

Shapley Attribution

Know exactly which studies drove every meta-analytic conclusion. Game-theoretic attribution surfaces the evidence that matters most, and why.

Planned

Evidence Studio

Collaborative workspace for distributed review teams. Real-time conflict resolution, annotation and consensus workflows built for multi-site trials.

Vision

Evidence Orchestrator

A multi-agent pipeline that autonomously searches, screens, extracts and synthesizes; fully auditable, with human checkpoints at every critical junction.

Want early access to upcoming features?

Talk to the Team

Ready to Accelerate Your Evidence Workflow?

Book a Demo